What Is Total Leucocyte Count (TLC) meaning, Procedure, normal value, clinical significance.
Total Leucocyte Count (TLC): Procedure, Calculation, and Clinical Significance Introduction Total Leucocyte Count (TLC) refers to the total number of white blood cells (WBCs) present in 1 microliter (µL) of blood. WBCs are crucial components of the immune system, responsible for defending the body against infections, foreign substances, and abnormal cells. Table of content Introduction Normal TLC range in adults Required Equipment for TLC Estimation Reagents Used Method for Estimating Total Leucocyte Count Calculation of TLC Clinical Applications and Interpretation Common Clinical Uses: Precautions Conclusion Normal TLC range in adults : 4,000 – 11,000 WBCs/µL of blood Abnormal TLC can indicate infections, inflammations, immune system disorders, or bone marrow abnormalities. Required Equipment for TLC Estimation 1. Neubauer’s Hemocytometer (Improved Neubauer chamber) 2. WBC pipette 3. Turk’s fluid (Diluting fluid containing glacial acetic acid and gentian viole...